Modeling nanofiber transport and deposition in human airways
"An understanding of the complex motion of fibrous particles is importantin a wide range of areas, including inhalation toxicology, targeted drugdelivery, composites manufacturing, paper making, and food processing.While the applications are diverse, the governing equations for the fibermotion...
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| Institution: | ETUI-European Trade Union Institute |
| Format: | TEXT |
| Language: | English |
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Luleå University of Technology
2010
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| Online Access: | https://www.labourline.org/KENTIKA-19183053124919012359-Modeling-nanofiber-transport-a.htm |
| Summary: | "An understanding of the complex motion of fibrous particles is importantin a wide range of areas, including inhalation toxicology, targeted drugdelivery, composites manufacturing, paper making, and food processing.While the applications are diverse, the governing equations for the fibermotion may be shared.
Fiber transport and deposition properties are determined by particlecharacteristics, flow pattern and bounding geometry. One of the mostimportant mechanical parameters is particle size, and while there arequite many publications on the behavior of micron particles, there arefew covering nanoparticles. Further, most studies are limited to particlesof spherical shape.
This project was originally initiated to gain information regardinghealth risks associated with inhalation of carbon nanotubes. Thus, thecore of the thesis is concerned with particle inhalation and deposition inlung flows, but the theory developed and the knowledge acquired is alsoapplied to fiber flows related to composites manufacturing. The problemis addressed by the use of theoretical models accompanied by numericalsimulations, and a considerable part of the total work was devoted to thedevelopment of a model for the combined translational and rotationalmotion of a fibrous particle in an arbitrary flow and geometry…" |
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| Physical Description: | 227 p. Paper Digital |